About UNICORN


Introduction

This section is a general overview of the UNICORN system.


What is UNICORN?

UNICORN is a complete package for control and supervision of chromatography systems. It consists of control software and a controller card for interfacing the controlling PC to the chromatography liquid handling module.

Liquid chromatography is used in separation processes, for analytical purposes or in the biochemical process industry.

UNICORN is a trademark of GE Healthcare.


Operating environment

UNICORN runs on a PC under Microsoft® Windows® 2000 or Microsoft Windows XP. It is designed to run under English keyboard settings.


Windows functions

Most Windows functions are also available in UNICORN, including

  • cut and paste

  • right-click short-cut menus

Note: Drag and drop is not available. File and folder handling in UNICORN also differs from the general Windows file manager standard.


Bar code reader

You can connect a bar code reader to the PC and use the reader to enter information instead of using the keyboard. This can be useful for example when entering information like batch IDs.


Compatible chromatography systems

UNICORN can be used with a number of systems including

  • ÄKTA™ design systems

  • BioProcess™ systems

Note: All examples in this guide are based on an ÄKTAexplorer™ 100 system that operates with the E100F400 strategy.If you use another system you may find that the descriptions and instructions do not match your system on every point. In that case you also need to refer to the user documentation for your specific chromatography system.


System networks

UNICORN can be installed on a stand-alone computer to control only a single, locally attached system. However, a stand-alone computer can control up to four separate systems. In a network installation each computer workstation can operate many systems regardless if they are locally connected or not. Each system can only be operated by one workstation at a time, but several may view the output data.


Software modules

The UNICORN control software consists of four integrated modules:

Module

Function

UNICORN Manager

File handling and administration, e.g. definition of systems and user profile etc.

Method Editor

To create and edit methods for pre-programmed control of chromatography systems.

System Control

To control and monitor the separation processes online, through method-based or manual control.

Evaluation

To evaluate and present stored results from separation processes.

Note: All modules are active when the program is operating, and are not closed when they are minimized. A minimized System Control unit may control a process. All modules will normally open when the program is started. However, a user profile may be set up so that not all modules are available. Only the available modules will be displayed.


Work flow

The work flow in UNICORN can be divided into four distinct stages. Each stage is described in separate chapters in this manual. The flow chart below shows the work flow stages.


Help functions

An online help utility is included in the UNICORN software. The table below describes how to access the help utility.

If you want to access...

Then...

the general help utility.

open the Help menu in any of the software modules.

context-specific help topics.

  • click the Help button in the dialog box

or

  • press the F1 key on your keyboard.

the online manuals.

open the Help menu in any of the software modules and select Manuals.


Security

The table below describes the main security functions in UNICORN:

Feature

Function

Access Security

Only authorized users can access UNICORN. Each user is assigned an access level, which defines the functions that the user is permitted to use.

Connection Security

A running system can only be controlled from one connection. Systems may be locked with a password to prevent other, un-authorized users from changing parameters.

Data Security

Result files from an ongoing separation run can be saved automatically at preset intervals to minimize data loss if the system fails. The results are saved locally if the network communication fails.

Electronic Signatures

Method and result files can be signed electronically for enhanced security and accountability.


2005-06-15