This thesis is based on the following articles, which will be referred to by their Roman numerals.
| I. | Jeltsch, M.*, Kaipainen, A.*, Joukov, V., Meng, X., Lakso, M., Rauvala, H., Swartz, M., Fukumura, D., Jain, R. K. and Alitalo, K. (1997): Hyperplasia of lymphatic vessels in VEGF-C transgenic mice [published erratum appeared 1997 in Science 277, 463]. Science 276, 1423-1425. | |
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| II. | Oh, S. J., Jeltsch, M. M., Birkenhager, R., McCarthy, J. E., Weich, H. A., Christ, B., Alitalo, K. and Wilting, J. (1997): VEGF and VEGF-C: specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane. Developmental Biology 188, 96-109. | |
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| III. | Achen, M. G., Jeltsch, M., Kukk, E., Makinen, T., Vitali, A., Wilks, A. F., Alitalo, K. and Stacker, S. A. (1998): Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4). Proceedings of the National Academy of Science of the USA 95, 548-553. | |
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| IV. | Jeltsch, M., Karpanen, T. and Alitalo, K. (manuscript submitted, 2002): Identification of VEGF receptor specificity determinants using VEGF - VEGF-C mosaic molecules. | |
*These authors contributed equally to this work.