Program

Program at a glance

Sunday, June 3, 2018
     
17:00-19:30   Opening ceremony & Plenary session I
    Co-sponsored by Aerpio Pharmaceuticals - Targeting the Tie2 pathway for novel therapeutics
    Finlandia Main Hall
     
    Chairs: Lena Claesson-Welsh, Pipsa Saharinen, Kari Alitalo & Christer Betsholtz
     
17:30-18:10   Napoleone Ferrara (San Diego, CA, USA)
    Current state of anti-angiogenic therapies
18:10-18:50   Susan Quaggin (Chicago, IL, USA)
Stolen identities - new vascular phenotypes Tie'd to disease
18:50-19:30   Helen Hobbs (Dallas, TX, USA)
    ANGPTLs, lipid metabolism and energy homeostasis
   
19:30   Welcome Reception at Finlandia Hall

Monday, June 4, 2018
     
8:30-9:50   Plenary session II
    Sponsored by Aerpio Pharmaceuticals - Targeting the Tie2 pathway for novel therapeutics
    Finlandia Main Hall
     
    Chairs: Hellmut Augustin & Luisa Iruela-Arispe
     
8:30-9:10   Elisabetta Dejana (Milan, Italy & Uppsala, Sweden)
    Transcriptional regulation of the brain microvasculature
9:10-9:50   Gou Young Koh (Daejeon, Korea)
    Organotypic vasculatures: maintenance and pathophysiology
     
9:50-10:15   Coffee Break

    Parallel sessions 1-4
     
10:15-12:15   Parallel session 1: Atherosclerosis
    Sponsored by the Japanese Vascular Biology and Medicine Organisation
    Helsinki Hall
     
    Chairs: Yvonne Alexander & Petri Kovanen
     
10:15-10:45   Klaus Ley (La Jolla, CA, USA)
    T cell immune response in atherosclerosis
10:45-11:15   Masayuki Yoshida (Tokyo, Japan)
    A novel role of neutrophils in vascular inflammation and atherosclerosis induced by high fat diet
11:15-11:45   Tetsuya Matoba (Fukuoka, Japan)
    Role of oxysterols in endothelial dysfunction and atherothrombosis
     
11:45-12:00   Short talk: Yun Fang (Chicago, IL, USA)
    Coronary artery disease locus 1p32.2 harbors a flow-sensitive endothelial enhancer that regulates PLPP3
12:00-12:15   Short talk: Kim Pin Yeo (Singapore, Singapore)
    Aortic lymphatic vessel: for or against atherosclerosis in experimental models?

10:15-12:15   Parallel session 2: Blood brain barrier
    Veranda 1
     
    Chairs: Jean-Leon Thomas & Berislav Zlokovic
     
10:15-10:45   Calvin Kuo (Stanford, CA, USA)
    Molecular regulation of the blood-brain barrier
10:45-11:15   Berislav Zlokovic (Los Angeles, CA, USA)
    Alzheimer's disease: A matter of dysfunction of the blood-brain barrier?
11:15-11:45   Injune Kim (Daejeon, Korea)
    Signalings for adult blood-retina barrier maintenance
     
11:45-12:00   Short talk: Patric Turowski (London, UK)
    VEGF receptor signalling in the leaky neural endothelium
12:00-12:15   Short talk: Christian Ramakers (Leiden, The Netherlands)
    BBB on-a-chip: a 3D in vitro model of the human blood brain barrier (BBB)

10:15-12:15   Parallel session 3: TIE2 pathway in vascular disease
    Sponsored by Aerpio Pharmaceuticals - Targeting the Tie2 pathway for novel therapeutics
    Veranda 2
     
    Chairs: Samir Parikh & Susan Quaggin
     
10:15-10:45   Hellmut Augustin (Heidelberg, Germany)
    Mechanisms of vascular maturation and quiescence
10:45-11:15   Pipsa Saharinen (Helsinki, Finland)
    New mechanisms of vascular leakage
11:15-11:45   Dietmar Vestweber (Münster, Germany)
    Mechanisms that regulate leukocyte diapedesis and endothelial junctions
     
11:45-12:00   Short talk: Sarah Mueller (Durham, NC, USA)
    The scaffolding protein Caskin2 regulates vascular homeostasis downstream of Angiopoietin/Tie receptor signaling
12:00-12:15   Short talk: Elizabeth Jones (Leuven, Belgium)
    Shear stress and VE-cadherin: The molecular mechanism of vascular fusion

10:15-12:15   Parallel session 4: Metabolic disease
    Sponsored by Novo Nordisk
    Veranda 3
     
    Chairs: Zoltan Arany & Kenneth Walsh
     
10:15-10:45   Andreas Fischer (Heidelberg, Germany)
    Endothelial control of muscle cell metabolism
10:45-11:15   Hyo-Soo Kim (Seoul, Korea)
    Resistin - Cap1 axis in the pathogenesis of metabolic syndrome​
11:15-11:45   Ulf Eriksson (Stockholm, Sweden)
    Role of VEGF-B signaling in diabetic complications
     
11:45-12:00   Short talk: Xuri Li (Guangzhou, China)
    Novel function of VEGF-B in tethering the FGF2/FGFR1 pathway
12:00-12:15   Short talk: Peppi Koivunen (Oulu, Finland)
    Lower hemoglobin levels associate with lower body mass index and healthier metabolic profile
12:15-12:45   Lunch
12:30-13:00   Lunch Seminar
    Sponsored by Aerpio Pharmaceuticals - Targeting the Tie2 pathway for novel therapeutics
     
    Chairs: Kevin Peters (Cincinnati, OH, USA)
     
12:30-13:00   Peter Campochiaro (Baltimore, MD, USA)
    Targeting the Tie2 pathway for retinal and choroidal vascular diseases
     
12:45-14:15   Poster session I

    Parallel sessions 5-8
     
14:15-16:00   Parallel session 5: Vascular inflammation
    Helsinki Hall
     
    Chairs: Jozef Dulak & Dietmar Vestweber
     
14:15-14:45   Beat Imhof (Geneve, Switzerland)
    Novel mechanisms in acute and chronic vascular inflammation
14:45-15:15   Sirpa Jalkanen (Turku, Finland)
    New tools to prevent vascular leakage
15:15-15:45   Britta Engelhardt (Bern, Switzerland)
    Brain barriers control immune surveillance of the CNS
     
15:45-16:00   Short talk: Jennifer Gamble (Sydney, Australia)
    Therapeutic manipulation of VE-cadherin

14:15-16:00   Parallel session 6: Mechanotransduction & ECM
    Veranda 1
     
    Chairs: Tatiana Byzova & Claudio Franco
     
14:15-14:45   Stefan Offermanns (Bad Nauheim, Germany)
    GPCRs and downstream signaling in endothelial mechanotransduction
14:45-15:15   Martin A. Schwartz (New Haven, CT, USA)
    Fluid shear stress in endothelial phenotype and function
15:15-15:45   Yu Huang (Hong Kong, China)
    Endothelial mechanical stress, inflammation and atherogenesis
     
15:45-16:00   Short talk: Anne-Clemence Vion (Nantes, France)
    Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression

14:15-16:00   Parallel session 7: Vessel development & stability
    Sponsored by Aerpio Pharmaceuticals - Targeting the Tie2 pathway for novel therapeutics
    Veranda 2
     
    Chairs: Christopher Kontos & Anna Randi
     
14:15-14:45   Samir Parikh (Boston, MA, USA)
    Coagulation and hemostasis during inflammation
14:45-15:15   Yvonne Reiss (Frankfurt am Main, Germany)
    Improved survival in a glioblastoma model by a combination of anti-angiogenic and immune checkpoint therapy
15:15-15:45   Yulong He (Jiangsu, China)
    Tie2 in the regulation of angiogenesis and lymphatic formation
     
15:45-16:00   Short talk: Lauri Eklund (Oulu, Finland)
    Venous specific development and fluid homeostasis in the retina

14:15-16:00   Parallel session 8: Lymphatic specification & morphogenesis
    Veranda 3
     
    Chairs: Dontscho Kerjaschki & Taija Mäkinen
     
14:15-14:45   Guillermo Oliver (Chicago, IL, USA)
    Lumen formation and maintenance in the lymphatic vasculature
14:45-15:15   Natasha Harvey (Adelaide, Australia)
    Dissecting gene function in lymphatic vessel morphogenesis
15:15-15:45   Friedemann Kiefer (Münster, Germany)
    Importance of VE-cadherin in the maintenance of specific lymphatic vessel beds
     
15:45-16:00   Short talk: Michael Jeltsch (Helsinki, Finland)
    All you ever wanted to know about vascular endothelial growth factor-C processing

16:00-16:30   Coffee Break
16:30-17:50   Plenary session III
    Co-sponsored by Aerpio Pharmaceuticals - Targeting the Tie2 pathway for novel therapeutics
    Finlandia Main Hall
     
    Chairs: Ralf Adams & Debabrata Mukhopadhyay
     
16:30-17:10   Holger Gerhardt (Berlin, Germany)
    Principles and regulation of endothelial cell dynamics in angiogenesis
17:10-17:50   Naoki Mochizuki (Osaka, Japan)
    Ang1/Ang2-Tie1/Tie2 signaling for hematovascular development in zebrafish
     
18:30-20:00   Reception at Helsinki City Hall

Tuesday, June 5, 2018
     
8:30-9:50   Plenary session IV
    Finlandia Main Hall
     
    Chairs: Jan Kitajewski & Curzio Rüegg
     
8:30-9:10   Anne Eichmann (New Haven, CT, USA), The EMBO Keynote Lecture
    Guidance of organ-specific vascular patterning
9:10-9:50   Rakesh Jain (Boston, MA, USA)
    Reengineering the tumor microenvironment to improve cancer treatment: Bench to bedside
     
9:50-10:15   Coffee Break

    Parallel sessions 9-12
     
10:15-12:15   Parallel session 9: Neurovascular interactions & disease
    Helsinki Hall
     
    Chairs: Christer Betsholtz & Britta Engelhardt
     
10:15-10:45   Jaime Grutzendler (New Haven, CT, USA)
    In vivo optical interrogation of neurovascular function and pathology
10:45-11:15   Chenghua Gu (Boston, MA, USA)
    Interactions of nervous and vascular systems
11:15-11:45   Jonathan Kipnis (Charlottesville, VA, USA)
    Meningeal lymphatic network in CNS pathologies
     
11:45-12:00   Short talk: Bong-Ihn Koh (Daejeon, Korea)
    Brain photothrombotic injury induces VEGF-dependent pathologic angiogenesis and sustained vascular leakage
12:00-12:15   Short talk: Laurent Jacob (Paris, France)
    Volume imaging of the rachis lymphatic network in rodents

10:15-12:15   Parallel session 10: Endothelial cell metabolism & angiogenesis
    Veranda 1
     
    Chairs: Riikka Kivelä & William Sessa
     
10:15-10:45   Zoltan Arany (Philadelphia, PA, USA)
    The peculiarities of endothelial metabolism
10:45-11:15   Michael Potente (Bad Nauheim, Germany)
    Metabolite signalling in the vascular endothelium
11:15-11:45   Peter Carmeliet (Leuven, Belgium)
    Angiogenesis revisited: role and (therapeutic) implications of endothelial metabolism
     
11:45-12:00   Short talk: Bernard M. van den Berg (Leiden, the Netherlands)
    Endothelial glucose metabolism regulates glycocalyx hyaluronan synthesis and thereby vessel stability
12:00-12:15   Short talk: Debabrata Mukhopadhyay (Jacksonville, FL, USA)
  Neuropilin-1 maintains dimethylarginine dimethylaminohydrolase 1 expression in endothelial cells and regulates angiotensin II induced-hypertension

10:15-12:15   Parallel session 11: Vascular Signalling
    Sponsored by Eli Lilly
    Veranda 2
     
    Chairs: Xuri Li & Lena Claesson-Welsh
     
10:15-10:45   Young-Guen Kwon (Seoul, Korea)
    CLEC14A in regulation of VEGFR-dependent signals in the vasculature
10:45-11:15   Tetsuro Watabe (Tokyo, Japan)
    TGF-β family signals in the formation and maintenance of vascular systems
11:15-11:45   Lars Jakobsson (Stockholm, Sweden)
    Endoglin in regulation of vascular patterning and malformation
     
11:45-12:00   Short talk: Emma Gordon (St. Lucia, Australia)
    Dynamic cell rearrangements guiding vascular growth and stability
12:00-12:15   Short talk: Suk-won Jin (New Haven, CT, USA)
    ACVR1/ALK2 enables venous selective pro-angiogenic responses to BMP signaling

10:15-12:15   Parallel session 12: Targeting tumor vasculature
    Sponsored by The Swedish Childhood Cancer Foundation
    Finlandia Main Hall
     
    Chairs: Sudhakar Chintharlapalli & Yvonne Reiss
     
10:15-10:45   Michele De Palma (Lausanne, Switzerland)
    Reprogramming tumor blood vessels for enhancing cancer immunotherapy
10:45-11:15   Gabriele Bergers (Leuven, Belgium)
    High-endothelial venules in cancer
11:15-11:45   Donald McDonald (San Francisco, CA, USA)
    Vascular targeting by oncolytic vaccinia virus
     
11:45-12:00   Short talk: Stephen Moss (London, UK)
    Pre-clinical development and testing of Magacizumab, a therapeutic antibody against LRG1
12:00-12:15   Short talk: Radu V. Stan (Hanover, NH, USA)
  Plasmalemma vesicle associated protein (PLVAP) is a novel target for cancer immunotherapy
12:15-12:45   Lunch
     
12:45-14:15   Poster session II

    Parallel sessions 13-16
     
14:15-16:15   Parallel session 13: Cardiovascular disease
    Helsinki Hall
     
    Chairs: Michael Simons & Seppo Ylä-Herttuala
     
14:15-14:45   Riikka Kivelä (Helsinki, Finland)
    Paracrine regulation of endothelial-cardiomyocyte crosstalk in cardiac hypertrophy
14:45-15:15   Kenneth Walsh (Charlottesville, VA, USA)
    Somatic mutations that drive clonal hematopoiesis and vascular disease
15:15-15:45   Stefanie Dimmeler (Frankfurt am Main, Germany)
    Regulation of vascular growth by non-coding RNAs
     
15:45-16:00   Short talk: Thomas Korff (Heidelberg, Germany)
    NFAT5/TonEBP - a mechanosensitive transcription factor in vascular smooth muscle cells controlling arterial remodeling
16:00-16:15   Short talk: Claudio Franco (Lisbon, Portugal)
    Junctional forces and wall shear stress compete to coordinate collective endothelial cell polarity

14:15-16:15   Parallel session 14: Vascular smooth muscle cells
    Organized in collaboration with European Society of Cardiology
    Veranda 1
     
    Chairs: Marie-Luce Bochaton-Piallat & Magnus Bäck
     
14:15-14:45   Cecilia Giachelli (Seattle, WA, USA)
    Vascular calcification: new concepts in regulation and therapy
14:45-15:15   Gordon Francis (Vancouver, Canada)
    Smooth muscle cells: The silent majority of atherosclerotic lesion foam cells
15:15-15:45   Gary Owens (Charlottesville, VA, USA)
    IL1b signaling in smooth muscle cells plays a critical role in atherosclerotic lesion pathogenesis
     
15:45-16:00   Short talk: Muriel Laffarque (Toulouse, France)
    PI3Kγ-dependent T cell response delays endothelial healing and reveals a novel role for arterial CXCL10
16:00-16:15   Short talk: Angela Bradshaw (Glasgow, UK)
    TGFβ signaling via ALK1 and ALK5 regulates distinct functional pathways in vein graft intimal hyperplasia
     
16:30-18:30   European Society of Cardiology round table
    Veranda 1

14:15-16:15   Parallel session 15: Lymphangiogenesis
    Veranda 2
   
    Chairs: Agnes Noel & Tatiana Petrova
     
14:15-14:45   Taija Mäkinen (Uppsala, Sweden)
    Mechanisms of sprouting lymphangiogenesis
14:45-15:15   Stefan Schulte-Merker (Münster, Germany)
    Functional analysis of brain lymphatic endothelial cells
15:15-15:45   Ben Hogan (Brisbane, Australia)
    New mechanisms of lymphatic vascular development from zebrafish
     
15:45-16:00   Short talk: Raghu Kataru (New York, NY, USA)
    Critical role of tumor lymphatic function in regulating tumor inflammatory and immunosuppressive microenvironment
16:00-16:15   Short talk: Akira Takeda (Turku, Finland)
    A new type of lymphatic endothelial cells in the medulla of lymph nodes

14:15-16:15   Parallel session 16: Tumor angiogenesis
    Sponsored by The Swedish Childhood Cancer Foundation
    Finlandia Main Hall
     
    Chairs: Anna Dimberg & Eli Keshet
     
14:15-14:45   Gavin Thurston (Tarrytown, NY, USA)
    Delta-Notch interactions between stromal cells and tumor cells
14:45-15:15   Nobuyuki Takakura (Osaka, Japan)
    Vascular promotion by LPA4 activation improves the malignant tumor microenvironment
15:15-15:45   Kristian Pietras (Lund, Sweden)
    Blood vessel control of the malignant phenotype
     
15:45-16:00   Short talk: Amanda Lund (Portland, OR, USA)
    IFNγ-dependent activation of dermal lymphatic vessels limits cytotoxic immunity in malignant and inflamed skin
16:00-16:15   Short talk: Giorgio Seano (Paris, France)
    In vivo dynamics and targeting of vessel co-option in glioblastoma

16:15-16:45   Coffee Break
16:45-18:05   Plenary session V
    Finlandia Main Hall
     
    Chairs: Stephane Germain & Mark Kahn
     
16:45-17:25   William Sessa (New Haven, CT, USA)
    The interfaces of endothelial function and lipid metabolism
17:25-18:05   Ralf Adams (Münster, Germany)
    Vascular cell heterogeneity and functional specialization
     
18:10-19:10   Showcases
    Veranda 2
     
18:10-18:40   Pelle Larshammar, Bio-Rad Laboratories
    Using Droplet Digital™ PCR (ddPCR™) for Cancer and Liquid Biopsy Studies
18:40-19:10   Jean Habyarimana, Janvier Labs
Breeder's expertise and its contribution in cardio and vascular research
     
18:10-19:10   Meet the Editors
    Helsinki Hall
   
    Discussion Mediator: Dr. Hellmut Augustin
   
    Lise Roth, PhD
    Editor, EMBO Molecular Medicine
    Sarah Jackson, PhD
    Executive Editor, Journal of Clinical Investigation

Wednesday, June 6, 2018
     
8:30-9:50   Plenary session VI
    Finlandia Main Hall
     
    Chairs: Elisabetta Dejana & Vesa Kiviniemi
     
8:30-9:10   Maiken Nedergaard (Copenhagen, Denmark & Rochester, NY, USA)
    The glymphatic system
9:10-9:50   Mark Kahn (Philadelphia, PA, USA)
    Signaling pathways in vascular disease
     
9:50-10:15   Coffee Break

    Parallel sessions 17-20
     
10:15-12:15   Parallel session 17: Leukocyte trafficking & endothelial barrier function
    Helsinki Hall
     
    Chairs: Jennifer Gamble & David Jackson
     
10:15-10:45   Cornelia Halin (Zurich, Switzerland)
    Leukocyte migration through afferent lymphatic vessels
10:45-11:15   Jaap van Buul (Amsterdam, The Netherlands)
    How leukocytes cross the endothelium: the actin link
   
11:15-11:30   Short talk: Masataka Majima (Kanagawa, Japan)
    Microenvironmental BLT1-signaling facilitates tumor-associated angiogenesis via inducing mast cell recruitment
11:30-11:45   Short talk: William A. Muller (Chicago, IL, USA)
    The role of the PECAM/VE-cadherin/VEGFR2 mechanosensing complex in initiating transendothelial migration
11:45-12:00   Short talk: Arie Horowitz (Philadelphia, PA, USA)
    MPDZ trafficking underlies endothelial cell junction dynamics
12:00-12:15   Short talk: Mark Richards (Uppsala, Sweden)
    Identification of permeability permissive vessels and their molecular markers using correlative intravital imaging

10:15-12:15   Parallel session 18: Novel functions of lymphatic vessels
    Veranda 1
     
    Chairs: Mark Achen & Jörg Wilting
     
10:15-10:45   Barbara Garmy-Susini (Toulouse, France)
    Lymphatic system: a novel actor in cancer-associated cachexia
10:45-11:15   Ebba Brakenhielm (Rouen, France)
    Cardiac lymphangiogenesis in cardiovascular diseases
11:15-11:45   Dontscho Kerjaschki (Vienna, Austria)
    Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice
     
11:45-12:00   Short talk: Timothy Padera (Cambridge, MA, USA)
    Lymph node metastases as a source for distant metastases
12:00-12:15   Short talk: Agnès Noel (Liège, Belgium)
    uPARAP/endo180: a novel partner of VEGFR-2/R-3 that controls VEGF-C-induced lymphatic sprouting

10:15-12:15   Parallel session 19: Angiogenesis
    Veranda 2
     
    Chairs: Holger Gerhardt & Valentin Djonvo
     
10:15-10:45   Victoria Bautch (Chapel Hill, NC, USA)
    How blood vessels control their destiny
10:45-11:15   Yoshiaki Kubota (Tokyo, Japan)
    Cell-to-cell communication in retinal vascular development
11:15-11:45   Rui Benedito (Madrid, Spain)
    High mitogenic stimulus induced by VEGF or Notch inhibition arrests angiogenesis
     
11:45-12:00   Short talk: Alessandro Fantin (London, UK)
    Erythro-myeloid progenitors contribute endothelial cells to developing vasculature
12:00-12:15   Short talk: Osamu Nakagawa (Osaka, Japan)
    Significance of the Hey family of transcription factors during cardiovascular development

10:15-12:15   Parallel session 20: Mechanisms of vascular disease
    Veranda 3
     
    Chairs: Andreas Bikfalvi & Karen Hirschi
     
10:15-10:45   Michael Dellinger (Dallas, TX, USA)
    Lymphatic vessels and vanishing bones: characterization of an animal model of Gorham-Stout disease
10:45-11:15   Mariona Graupera (Barcelona, Spain)
    Role of oncogenic PI3K in endothelium-related diseases
11:15-11:45   Goo Taeg Oh (Seoul, Korea)
    Atherogenesis protection by a novel cytokine produced by alternatively activated macrophages
     
11:45-12:00   Short talk: Andrea Banfi (Basel, Switzerland)
    EphrinB2/EphB4 signaling regulates non-sprouting angiogenesis by VEGF
12:00-12:15   Short talk: Mia Phillipson (Uppsala, Sweden)
    Perivascular macrophages regulate blood flow following tissue damage
12:15-12:45   Lunch
     
12:45-14:15   Poster session III

    Parallel sessions 21-24
     
14:15-16:00   Parallel session 21: Organotypic vasculature
    Helsinki Hall
     
    Chairs: Natasha Harvey & Gou Young Koh
     
14:15-14:45   Bin Zhou (Shanghai, China)
    Genetic targeting of organ specific endothelial cells
14:45-15:15   Tatiana Petrova (Lausanne, Switzerland)
    Organ-specific features and control of lymphatic vasculature
15:15-15:45   Karina Yaniv (Rehovot, Israel)
    Differentiation of endothelial cells and formation of organ-specific vascular beds
     
15:45-16:00   Short talk: Mahak Singhal (Heidelberg, Germany)
    Endothelial cell fitness dictates the source of regenerating liver vasculature

14:15-16:00   Parallel session 22: Endothelial regeneration & senescence
    Veranda 1
     
    Chairs: Lauri Eklund & Shahin Rafii
     
14:15-14:45   Jun K. Yamashita (Kyoto, Japan)
    Blood vessels for tissue regeneration
14:45-15:15   Luisa Iruela-Arispe (Los Angeles, CA, USA)
    Molecular mechanisms of endothelial regeneration
15:15-15:45   Mike Sapieha (Montreal, Canada)
    Cellular senescence and angiogenesis
     
15:45-16:00   Short talk: Mei Xin (Cincinnati, OH, USA)
    Hippo signaling effector Yap regulates hyaloid vasculature regression in the developing eye

14:15-16:00   Parallel session 23: Vascular physiology & pathology
    Veranda 2
     
    Chairs: Timothy Hla & Levon Khachigian
     
14:15-14:45   Ingrid Fleming (Frankfurt am Main, Germany)
    Inhibition of soluble epoxide hydrolase stabilizes endothelial cell-pericyte interactions and prevents diabetic retinopathy
14:45-15:15   Randall S. Johnson (Cambridge, UK & Stockholm, Sweden)
    The role of hypoxic response in vascular function
15:15-15:45   Helge Wiig (Bergen, Norway)
    Extrarenal interstitial sodium storage in extracellular volume and blood pressure homeostasis
     
15:45-16:00   Short talk: Leigh Coultas (Victoria, Australia)
    'Vessel reassembly' in the absence of endothelial apoptosis as a mechanism for revascularising ischemic retinas

14:15-16:00   Parallel session 24: Epigenetics & genetics of vascular differentiation
    Veranda 3
     
    Chairs: Graeme Birdsey & Risto Kerkelä
     
14:15-14:45   Michael Detmar (Zurich, Switzerland)
    Epigenetic control of vascular differentiation and function
14:45-15:15   Anna Randi (London, United Kingdom)
    Transcriptional and epigenetic control of endothelial and tissue homeostasis
     
15:15-15:30   Short talk: Stefania Nicoli (New Haven, CT, USA)
    MicroRNA-dependent regulation of biomechanical genes establish tissue stiffness homeostasis
15:30-15:45   Short talk: Minna Kaikkonen-Määttä (Kuopio, Finland)
    Developmentally regulated chromatin interactions orchestrate transcriptional changes in endothelial cells during vasculogenesis and angiogenesis
15:45-16:00   Short talk: Ilse Luyckx (Antwerpen, Belgium)
    SMAD2 and SMAD6: two novel genetic players in aortic aneurysm and dissection

16:00-16:30   Coffee Break
16:30-18:50   Plenary session VII & Workshop
    Finlandia Main Hall
     
    Chairs: Gary Owens & Nobuyuki Takakura
     
16:30-17:10   Michael Simons (New Haven, CT, USA)
    Disease pathogenesis and cell fate: the tale of two cell types
     
17:10-18:40   Workshop on Vascular Single-Cell RNA Sequencing
    Investigators from the vascular biology field will present their latest results and discuss technological challenges and bioinformatics methods in single-cell RNA sequencing.
17:10-17:40   Sten Linnarsson (Stockholm, Sweden)
    Inferring cell types and lineages of the mammalian brain from single-cell transcriptomes
17:40-17:55   Christer Betsholtz (Uppsala, Sweden)
    Defining mural cell types by single cell RNA sequencing
17:55-18:10   Short talk: Kevin Brulois (Stanford, CA, USA)
    Single-cell transcriptomics of lymphoid tissue blood endothelial cells
18:10-18:25   Short talk: Qi Zhao (Tarrytown, NY, USA)
    Sequencing tumor endothelial cells with 10x Genomics single cell platform
18:25-18:40   Short talk: Michael Vanlandewijck (Uppsala, Sweden)
    Blood-brain barrier single-cell transcriptomics with SmartSeq2
     
18:40-18:50   Presentation of IVBM2020 in Seoul
    Hyo-Soo Kim & Gou Young Koh
     
19:00-   Nordic Night at Allas Sea Pool

Thursday, June 7, 2018
     
    Parallel sessions 25-28
     
8:30-9:30   Parallel session 25: Vascular anomalies
    Helsinki Hall
     
    Chairs: Michael Dellinger & Mariona Graupera
     
8:30-9:00   Joyce Bischoff (Boston, MA, USA)
    GNAQ mutant endothelial cells in capillary malformations
9:00-9:30   Miikka Vikkula (Brussels, Belgium)
    Signaling defects in fast-flow vascular anomalies

8:30-9:30   Parallel session 26: Clinical translation
    Sponsored by Herantis Pharma
    Veranda 1
   
    Chairs: Andrea Banfi & Michael Detmar
     
8:30-9:00   Seppo Ylä-Herttuala (Kuopio, Finland)
    VEGFs in therapeutic vascular growth and beyond
9:00-9:30   Anne Saarikko (Helsinki, Finland)
    New therapeutic tools for lymphedema treatment

8:30-9:30   Parallel session 27: Arteriogenesis
    Veranda 2
     
    Chairs: Victoria Bautch & Jun Yamashita
     
8:30-9:00   Kristy Red-Horse (Stanford, CA, USA)
    Arteriogenesis during cardiac development and injury
9:00-9:30   Ferdinand Le Noble (Karlsruhe, Germany)
    Flt1 determines lumen formation during arteriogenesis

8:30-9:30   Parallel session 28: Fluid shear stress regulation
    Veranda 3
     
    Chairs: Injune Kim & Martin Schwartz
     
8:30-9:00   Young-Kwon Hong (Los Angeles, CA, USA)
    Regulation of lymphatic development by fluid flow
9:00-9:30   Arndt Siekmann (Münster, Germany)
    Investigating the role of hemodynamic forces in embryonic blood vessel patterning
     
9:30-10:00   Coffee Break
10:00-12:30   Plenary session VIII
    Sponsored by Regeneron Pharmaceuticals
    Finlandia Main Hall
   
10:00-10:20   Poster/Travel awards ceremony, awards sponsored by LE&RN, NAVBO, EVBO, French Angiogenesis Society, EMBO Molecular Medicine, JVBMO & Wihuri Research Institute
     
    Chairs: Naoki Mochizuki & Bin Zhou
     
10:20-11:00   Shahin Rafii (New York, NY, USA)
    Molecular determinants of vascular heterogeneity development
11:00-11:40   Didier Stainier (Bad Nauheim, Germany)
    Vascular development in zebrafish and mouse
11:40-12:20   Timothy Hla (Boston, MA, USA)
    Signaling and gene expression mechanisms of endothelial injury
   
12:20-12:30   Closing words

Program at a glance

Program at a glance